Cinnamic acids and derivatives
Medchemexpress LLC M-coumaric acid | 588-30-7 | 99.8% | 164.16 | 1 ML
m-Coumaric acid is an endogenous metabolite and polyphenol that is formed from caffeic acid by gut microflora. It is a BBB-penetrant metabolite of chlorogenic acid and can stimulate cerebral nerves and evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation. It has also been shown to increase spontaneous locomotor activity in mice.
- Inhibits the oxidation of L-dopa by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Stimulates cerebral nerves in vitro
- Promotes neuronal differentiation
- Increases spontaneous locomotor activity
Medchemexpress LLC 3,4,5-Trimethoxycinnamic acid | 90-50-6 | 99.9% | 238.24 | 25 G
3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of *Polygala tenuifolia WILLD*. It has an anti-stress effect and can prolong sleeping time in animals. This compound increases the expression of GAD65 and the γ-subunit of the GABAA receptor, but it does not affect the amounts of α- and β-subunits.
- Anti-stress effect
- Prolongs sleeping time in animals
- Increases expression of GAD65 and γ-subunit of GABAA receptor
- Exhibits sedative effect in rats
- Significantly decreases locomotor activity in mice
- Available in solid form, white to off-white color
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 50 MG
Ferulic acid 4-O-sulfate is a metabolite of Ferulic acid that relaxes arteries and lowers blood pressure in mice. This compound causes significant concentration-dependent relaxations in mouse aorta, femoral and saphenous arteries.
- Relaxes arteries and lowers blood pressure
- Suitable for in vitro and in vivo studies
- Significant concentration-dependent relaxations in mouse arteries
Selleck Chemical LLC 3.4.5-Trimethoxycinnamic acid S4961-25mg
3 4 5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | 99.8% | C14H11FO2 | 100 G
4-(3-Fluorobenzyloxy)benzaldehyde is a chemical compound that serves as a drug intermediate. It is used in the synthesis of various active compounds for research purposes.
- Solid appearance
- Functions as a drug intermediate
- Suitable for the synthesis of active compounds
- For research use only
- Shipped at room temperature in continental US
- Store at 4°C under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | MFCD02605317 | 99.82% | C14H11FO2 | 50 G
4-(3-Fluorobenzyloxy)benzaldehyde is a drug intermediate used for the synthesis of various active compounds. This product is provided as a solid and is intended for research use only.
- Drug intermediate for synthesis of active compounds
- Provided as a solid
- For research use only
Medchemexpress LLC Trans-cinnamic acid (standard) | 140-10-3 | 148.16 | 50 MG
trans-Cinnamic acid (Standard) serves as an analytical standard for research and analytical applications. It acts as a natural antimicrobial and is suitable for various laboratory experiments including HPLC, GC, and MS, as a reference standard assay.
- Analytical standard for trans-Cinnamic acid.
- Intended for research and analytical applications.
- Natural antimicrobial with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1.
- Used as a reference standard assay.
- Utilized in qualitative, quantitative, and methodological research experiments.
- Compatible with techniques such as HPLC, GC, and MS.
Medchemexpress LLC cis-Ferulic acid 4-O-β-D-glucopyranoside | 94942-20-8 | 356.32 | 1 MG
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycoside that can be isolated from Nitraria sibirica. It exhibits antioxidant activity and a potent inhibitory effect on Phosphatase PTP1B.
- Phenolic glycoside
- Isolated from Nitraria sibirica
- Exhibits antioxidant activity
- Potent inhibitory effect on Phosphatase PTP1B
Medchemexpress LLC p-Coumaric acid-13C3 | 1261170-80-2 | 167.14 | 1 MG
p-Coumaric acid-13C3 is the 13C-labeled version of p-Coumaric acid. p-Coumaric acid is a prevalent isomer of cinnamic acid, known for its antitumor and anti-mutagenic properties. This compound is intended for research use only and is not sold to patients. Stable heavy isotopes, including carbon, are incorporated into drug molecules primarily as tracers for quantification during drug development. Deuteration, in particular, has gained attention for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ferulic acid acyl-β-D-glucoside | 7196-71-6 | 1 ML
Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid that can be isolated from flaxseed extract. It is identified as a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor and is intended for research use only.
- Metabolite of Ferulic Acid
- Can be isolated from flaxseed extract
- Inhibits fibroblast growth factor receptor 1 (FGFR1) and FGFR2
- Purity: 99.33%
- Appearance: White to off-white solid
- Soluble in water (50 mg/mL)
- Soluble in PBS (25 mg/mL)
- Initial source from plants (Rosaceae, Aruncus sylvester Kostel.)
Medchemexpress LLC p-Coumaric acid (trans-4-Hydroxycinnamic acid) | 501-98-4 | 164.16 | 500 MG
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity that exhibits several biological activities:
- Inhibits cell proliferation
- Promotes apoptosis
- Has antibacterial activity
- Has anti-inflammatory activity
- Has antioxidant activity
- Has anti-tumor activities
Medchemexpress LLC 4-chlorocinnamic acid | 1615-02-7 | MFCD00004396 | 100.0% | 182.61 | C9H7ClO2 | 50g
4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A) 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0 477 mM and 0 229 mM respectively 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4]
Medchemexpress LLC Ferulic acid (standard) | 1135-24-6 | 100.0% | 10 MG
Ferulic acid (standard) is an analytical reference standard intended for qualitative and quantitative research, method development, and instrument calibration in chromatography and mass spectrometry. It is provided at defined high purity for reproducible analytical results.
- Analytical standard for HPLC, GC, and MS applications.
- High purity, suitable for quantitative analysis.
- CAS number 1135-24-6 for unambiguous identification.
- Molecular weight 194.18 and formula C10H10O4.
- Available in small quantities suitable for laboratory method development and calibration.
Cayman Chemical FerulIc AcId methyl ester 1g
A lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes; at 10-25 UG/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces NO generation from LPS-stimulated macrophages
eMolecules 2062-25-1 | 2-(Trifluoromethyl)cinnamicacid | MFCD00004381 | 25g
Pharmablock | ethyl (1E)-N-(246-trimethylphenyl)sulfonyloxyethanimidate | 2.5g | 794216768 | PBT1480 | 38202-27-6 | MFCD00009244 | 285.360 | C13H19NO4S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>