Cinnamic acids and derivatives
Medchemexpress LLC Tyrphostin AG 528 | 133550-49-9 | MFCD01076474 | 98.0% | 306.32 g·mol^-1 | C18H14N2O3 | 25 MG
Tyrphostin AG 528 is a small-molecule protein tyrosine kinase inhibitor used as a research reagent to probe EGFR and ErbB2 (HER2) signaling pathways. It is supplied as a high-purity solid for biochemical and cellular studies.
- Inhibits EGFR and ErbB2 with reported IC50s of 4.9 μM and 2.1 μM.
- High purity (98.0%) suitable for laboratory research.
- Supplied as a solid, light yellow to yellow in color.
- Molecular weight 306.32 g·mol⁻¹; formula C18H14N2O3.
- Available in small research quantities, including 25 mg packaging.
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 5mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 50mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Accela Chembio Inc 2-methylcinnamic Acid | Predominantly Trans | 25g | 2373-76-4 | MFCD00016841 | 97+% | Shelf Life: 1260 Days | Light Sensitive
2-methylcinnamic Acid | Predominantly Trans | 25g | 2373-76-4 | MFCD00016841 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Selleck Chemical LLC Curcumin S1848-10mM/1mL
Curcumin (Diferuloylmethane Natural Yellow 3 Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric which is a member of the ginger family (Zingiberaceae) It is an inhibitor of p300 histone acetylatransferase IC50 25 M and Histone deacetylase (HDAC) activates Nrf2 pathway and supresses the activation of NF- B Curcumin induces mitophagy autophagy apoptosis and cell cycle arrest with antitumor activity Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus hepatitis C virus HIV and so on
Medchemexpress LLC p-Coumaric acid (trans-4-Hydroxycinnamic acid) | 501-98-4 | 164.16 | 500 MG
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity that exhibits several biological activities:
- Inhibits cell proliferation
- Promotes apoptosis
- Has antibacterial activity
- Has anti-inflammatory activity
- Has antioxidant activity
- Has anti-tumor activities
Medchemexpress LLC p-Coumaric acid | 501-98-4 | MFCD00004399 | 164.16 | 5 G
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. It inhibits cell proliferation and promotes apoptosis. It also exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities.
- Inhibits cell proliferation
- Promotes apoptosis
- Exhibits antibacterial activity
- Exhibits anti-inflammatory activity
- Exhibits antioxidant activity
- Exhibits anti-tumor activities
Chem-Impex International, Inc. trans-4-Bromocinnamic acid | MFCD00004394 | 5G
trans-4-Bromocinnamic acid, MFCD00004394, 5G
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MM 1ML
SAR405 R enantiomer is the less active enantiomer of SAR405, a selective inhibitor of PIK3C3/Vps34, supplied for research use. It is offered as a ready-to-use 10 mM solution in DMSO or as a solid, and is used as a reference or control in studies of autophagy, vesicle trafficking, and related signaling pathways.
- Less active enantiomer of a PIK3C3/Vps34 inhibitor.
- High purity (~99.9%) for reliable experimental controls.
- Available as 10 mM solution in DMSO and multiple solid package sizes.
- Soluble in DMSO at 100 mg/mL; ultrasonication may be required.
- Storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
- Intended for research use only, not for clinical applications.
Cayman Chemical Plnt TurmerIc CurcumIn 10g
A yellow pigment with diverse biological activities; inhibits NO production (IC50 = 6 μM) and reduces iNOS activity in LPS-stimulated RAW 264.7 cells; inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells; decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis; prevents ovalbumin-induced accumulation of 3-NT in mouse heart; reduces TPA-induced tumor formation in mouse skin (1-10 μmol); reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-NQO in rats
Medchemexpress LLC 3-carboxy-6-hydroxycoumarin | 56437-16-2 | MFCD16295011 | 99.9% | 206.15 g/mol | C10H6O5 | 25 MG
3-Carboxy-6-hydroxycoumarin (CAS 56437-16-2) is a coumarin derivative used as an intermediate in organic synthesis. Supplied as a high-purity solid, it supports transformations that exploit the molecule's carboxyl and hydroxy functionalities for derivatization in medicinal chemistry and materials research.
Medchemexpress LLC Cinanserin hydrochloride | 54-84-2 | MFCD00055609 | 99.5% | 376.94 g/mol | C20H25ClN2OS | 5 MG
Cinanserin hydrochloride is a research-grade serotonin (5-HT2) receptor antagonist supplied as the hydrochloride salt for use in in vitro and preclinical pharmacology studies. It is provided as a solid suitable for assay development, receptor-binding studies, and biochemical experiments.
- Research-grade 5-HT2 receptor antagonist.
- Supplied as the hydrochloride salt in solid form.
- High purity (99.5%).
- CAS number 54-84-2.
- Molecular weight 376.94 g/mol.
- Intended for in vitro and preclinical research use.
- Store at 4 °C and protect from moisture.
Selleck Chemical LLC p-Coumaric Acid S4759-1g
p-Coumaric acid (4-Hydroxycinnamic acid P-Hydroxycinnamic acid 4-Coumaric acid Trans-p-Coumaric acid para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant anti-inflammatory and antimicrobial activity